https://learn-umbrella.cisco.com/i/802005-umbrella-security-report/3?
https://www.cisco.com/site/us/en/products/security/endpoint-security/secure-endpoint/index.html#:~:text=Powerful%20EDR%20capabilities,from%20Kenna%20Security.
Cisco Advanced Malware Protection (AMP) for endpoints can be seen as a replacement for the traditional antivirus solution. It is a next generation, cloud delivered endpoint protection platform (EPP), and advanced endpoint detection and response (EDR). Providing Protection - Detection Response While Cisco Umbrella can enforce security at the DNS-, IP-, and HTTP/S-layer, this report does not require that blocking is enabled and only monitors your DNS activity. Any malicious domains requested and IPs resolved are indicators of compromise (IOC).
Any malicious domains requested and IPs resolved are indicators of compromise (IOC)

Explanation:
The various suspicious patterns for which the Cisco Tetration platform looks in the current release are:
+ Shell code execution: Looks for the patterns used by shell code.
+ Privilege escalation: Watches for privilege changes from a lower privilege to a higher privilege in the process lineage tree.
+ Side channel attacks: Cisco Tetration platform watches for cache-timing attacks and page table fault bursts.
Using these, it can detect Meltdown, Spectre, and other cache-timing attacks.
+ Raw socket creation: Creation of a raw socket by a nonstandard process (for example, ping).
+ User login suspicious behavior: Cisco Tetration platform watches user login failures and user login methods.
+ Interesting file access: Cisco Tetration platform can be armed to look at sensitive files.
+ File access from a different user: Cisco Tetration platform learns the normal behavior of which file is accessed by which user.
+ Unseen command: Cisco Tetration platform learns the behavior and set of commands as well as the lineage of each command over time. Any new command or command with a different lineage triggers the interest of the Tetration Analytics platform.
Reference: https://www.cisco.com/c/en/us/products/collateral/data-center-analytics/tetration-analytics
/whitepaper-c11-740380.html

Explanation/Reference: https://docs.amp.cisco.com/en/A4E/AMP%20for%20Endpoints%20User%20Guide.pdf chapter 2

Cisco Defense Orchestrator is a cloud-based management solution that allows you to manage security policies and device configurations with ease across multiple Cisco and cloud-native security platforms.
Cisco Defense Orchestrator features:
....
Management of hybrid environments: Managing a mix of firewalls running the ASA, FTD, and Meraki MX software is now easy, with the ability to share policy elements across platforms.
Reference:
736847.html

The Cisco Umbrella Multi-Org console has the ability to upload, store, and archive traffic activity logs from your organizations' Umbrella dashboards to the cloud through Amazon S3. CSV formatted Umbrella logs are compressed (gzip) and uploaded every ten minutes so that there's a minimum of delay between traffic from the organization's Umbrella dashboard being logged and then being available to download from an S3 bucket.
By having your organizations' logs uploaded to an S3 bucket, you can then download logs automatically to keep in perpetuity in backup storage.