C. immitis is a dimorphic fungus which can be isolated from sputum specimens of infected individuals. When grown on Sabouraud's agar at 25o it grows as a mold with white aerial mycelium in about 3 to 5 days. C.
immitis is known to produce arthroconidia which are "barrel-shaped" after 1 to 2 weeks of growth.
Within three days at 28 ºC a sputum specimen placed on Sabouraud's dextrose agar with chloramphenicol and cycloheximide produced moist, grayish growth, with a white aerial mycelium, the organism is MOST likely:

Though it may not be required, TDM should still be used to confirm adequate dosing. Genotyping does not make TDM redundant.
A PM will metabolize the drug more slowly and therefore will need lower doses. CYP2D6 metabolizes many different drugs; it is not associated with just one class of drugs. Anytime a drug is taken that competes for the same metabolizing enzyme as another drug, there is potential for the concentrations of both drugs to be increased.
A patient has been characterized as a CYP2D6 poor metabolizer (PM) after genotyping. Which of the following statements is not true?

Cryoglobulin testing can be used to:

Infection early in the pregnancy is the most dangerous time period for the manifestation of anomalies due to rubella. In fact, defects are rare when infection occurs after 20 weeks gestation.
Immunology
The greatest risk for the manifestation of anomalies in maternal rubella infection during gestation is the:

In primary responses, the major class of antibody produced is IgM whereas in the secondary response, as mentioned in this question, it is IgG. IgG is present in the highest quantities compared to all other antibody classes and is the only antibody able to cross the placental barrier.
Which of the following antibody types is chiefly seen in the secondary immune response: