A patient is being discharged on dabigatran, and the pharmacotherapy specialist is counseling the patient's caregiver about the medication. What is the best information to give the caregiver concerning the storage of dabigatran?

The prophylaxis of postsurgical deep vein thrombosis was reviewed in an article published 5 years ago. A researcher wishes to identify any studies since then that have used this article as a reference. What is the most appropriate database for this search?

A study of oral contraceptive use found a risk of breast cancer in long-term (> 12 years) higher dose oral contraceptive users odds ratio = 2.33 (95% CI = 0.9-3.2). Which of the following statements most accurately assesses the study's conclusion that there is a modest effect of oral contraceptive use on breast cancer risk in young women?

A 59-year-old man presents to the neurology clinic with recently diagnosed Parkinson's disease.
At his last visit 2 months ago, selegiline therapy was instituted, and he is tolerating it well. The patient still complains of tremor and rigidity that are interfering with both professional and leisure activities. Which option is most appropriate at this time?

An obtunded 61-year-old Woman weighing 45 kg with Worsening renal function is admitted to the hospital. She has a recent history of several days of nausea, fatigue, pruritus, and a metallic taste in her mouth. Her medical history includes diabetes, heart failure, and COPD. Admission laboratory values include:
SERUM CHEMISTRY
Sodium: 135 mEq/L
Potassium: 5.7 mEq/L
Chloride: 100 mEq/L
HCO3: 15 mEq/L
BUN: 96 mg/dL
Creatinine: 5.5 mg/dL
Glucose: 300 mg/dL
Calcium: 7.4 mg/dL
Serum ketones: Negative
ABGS (Room Air)
pH: 72
PaCO2: 30 mm Hg
PaO2: 75 mm Hg
O2 Sat: 90%
Chest X-ray shows a flattened diaphragm. Current medications include furosemide, fluticasone salmeterol, and glipizide. Which acid-base disorder does this patient exhibit?