A three week old baby is brought in by her concerned parents She is vomiting substantially after feeds and is failing to gain weight. Investigation reveals an alkalosis and a low serum potassium.
The alkalosis is most likely to be due to which mechanism?

A 76 year old patient is found on examination to have an absent jaw jerk What cranial nerve nucleus is the1 most likely site of pathology?

A 15 year old girl with sickle cell anaemia attends with left leg swelling and pain Further investigations suggest a diagnosis of osteomyelitis of her tibia.
What is the most likely causative organism?

An 18 year old man presents with persistent vomiting You diagnose type I diabetes mellitus He asks you the implications of his diagnosis for driving a car What is the most accurate advice according to the DVLA?

A 71 year old man with a history of heart failure and type II diabetes mellitus presents with an acute, painful, swollen first metatarsophalangeal joint in his foot You suspect gout.
Which treatment would be most appropriate for the acute management of this patient*?