According to the SAP S/4HANA Cloud, public edition Learning Journey1, some changes that would prevent SAP from running automated business process tests on your behalf are: changes to the data input requirements (custom data fields); configuration changes that impact the process flow. Automated business process testing is a feature that allows you to test your business processes and scenarios in SAP S/4HANA Cloud using predefined test scripts and data. Changes to the data input requirements or the configuration settings may affect the validity or execution of the test scripts and data, and therefore require manual testing or adaptation.

Business users can create new analytics content by performing the following actions:
Create new data sources via joins of standard data sources. This allows users to combine data from different sources and create custom reports or dashboards.
Change existing data sources by adding filters. This allows users to refine the data selection and display only the relevant information.
Create additional key figures in existing data sources. This allows users to add new calculations or aggregations to the data and enhance the analysis. Reference: SAP Help Portal - Creating Analytics Content

If an out-of-the-box integration between SAP S/4HANA Cloud and another SAP solution is not available, you can use custom CDS views or integration tools to build your own integration. Unrestricted firewall and Infrastructure as a Service are not relevant for this scenario.