HPE SimpliVity allows customers to connect ESXi compute nodes to HPE SimpliVity datastores without additional license or configuration. This enables customers to leverage the data efficiency and protection features of HPE SimpliVity for their compute-intensive workloads. However, the compute nodes must reside in the same cluster as HPE SimpliVity nodes, and they must be authorized by HPE SimpliVity to access the NFS datastores. The number of compute nodes per cluster is limited by the maximum number of hosts supported by VMware vSphere. References: HPE SimpliVity User Guide; HPE SimpliVity Compute Node Software Installation and Startup Service

Before moving a virtual machine to another datastore, you need to take a snapshot of the virtual machine using the HPE SimpliVity plugin in vSphere. This ensures that the virtual machine is in a consistent state and that the data is protected. The snapshot also serves as a backup in case the move operation fails or is interrupted.
After taking the snapshot, you can use the HPE SimpliVity move operation to move the virtual machine to the desired datastore, either within the same cluster or across clusters. The move operation preserves the data efficiency and resiliency of the virtual machine, and does not require any downtime or reconfiguration12.
References: Move a virtual machine to another datastore - Hewlett Packard Enterprise, HPE SimpliVity frequently asked questions

According to the HPE SimpliVity 325 Gen10 QuickSpecs1, this model supports up to one NVIDIA Tesla T4 GPU accelerator. According to the HPE SimpliVity 380 Gen10 G Node QuickSpecs2, this model supports up to two NVIDIA Tesla T4 GPU accelerators. Therefore, these two models meet the customer needs for HPE SimpliVity nodes that support NVIDIA Tesla T4 GPUs.
The other models do not support NVIDIA Tesla T4 GPUs. According to the HPE SimpliVity 380 Gen10 QuickSpecs3, this model supports NVIDIA Tesla M10 and P40 GPUs, butnot T4 GPUs. According to the HPE SimpliVity 2600 QuickSpecs4, this model does not support any GPU accelerators. According to the HPE SimpliVity 380 Gen10 SFFH QuickSpecs, this model supports NVIDIA Tesla V100 and P100 GPUs, but not T4 GPUs. References:
1: HPE SimpliVity 325 Gen10 QuickSpecs,
https://h20195.www2.hpe.com/v2/getdocument.aspx?docname=a00073576enw
2: HPE SimpliVity 380 Gen10 G Node QuickSpecs,
https://h20195.www2.hpe.com/v2/getdocument.aspx?docname=a00073577enw
3: HPE SimpliVity 380 Gen10 QuickSpecs,
https://h20195.www2.hpe.com/v2/getdocument.aspx?docname=a00026086enw
4: HPE SimpliVity 2600 QuickSpecs,
https://h20195.www2.hpe.com/v2/getdocument.aspx?docname=a00026087enw
5: HPE SimpliVity 380 Gen10 SFFH QuickSpecs,
https://h20195.www2.hpe.com/v2/getdocument.aspx?docname=a00026088enw